Research Articles
Eliminating Dark Activity: Advanced Strategies for Optimizing OptoNodal Reagents in Biomedical Research
This article provides a comprehensive analysis of the strategies developed to minimize dark activity in optoNodal reagents, a critical challenge in optogenetic applications.
Light Patterning in Synthetic Embryology: Optogenetic Control of Signaling and Morphogenesis
This article explores the transformative role of light-patterning technologies in controlling synthetic signaling patterns within live embryos.
A Comprehensive Guide to optoNodal2: Protocol, Implementation, and Advanced Applications for Controlled Nodal Signaling
This article provides a detailed resource for researchers and drug development professionals on the next-generation optoNodal2 reagents for precise control of Nodal signaling.
Illuminating Gastrulation: Controlling Cell Internalization with Optogenetics
This article explores the transformative application of optogenetics to control cell internalization processes during gastrulation, a pivotal stage in embryonic development.
Ultra-Widefield Microscopy for Parallel Embryo Light Patterning: A Revolutionary Optogenetics Toolbox
This article explores the transformative potential of ultra-widefield microscopy for high-throughput optogenetic light patterning in embryonic research.
Optogenetic Control of Nodal Signaling in Zebrafish: A High-Throughput Pipeline for Embryonic Patterning and Biomedical Research
This article provides a comprehensive guide to an advanced optogenetic pipeline for precise spatiotemporal control of Nodal signaling in zebrafish embryos.
Decoding Positional Information in Embryos: From Morphogen Gradients to Precision Medicine
This article provides a comprehensive exploration of how cells interpret positional cues to form complex tissues and organs during embryonic development.
Signaling Dynamics in Gastrulation: Integrating Mechanics, Pathways, and Models for Developmental Biology and Drug Discovery
Gastrulation is a pivotal developmental stage where a uniform cell sheet transforms into the structured embryonic germ layers, a process long thought to be directed solely by biochemical signals.
Spatiotemporal Signaling in Cell Fate Decisions: From Dynamic Landscapes to Therapeutic Applications
This article synthesizes current research on how the spatial and temporal dynamics of cellular signaling govern cell fate decisions.
Spatial Multiomics: Mastering ISH and Immunohistochemistry Co-Localization for Precision Biomarker Discovery
This article provides a comprehensive guide to in situ hybridization (ISH) and immunohistochemistry (IHC) co-localization studies, a cornerstone of spatial biology.