Research Articles
RNAscope vs. HCR: A Strategic Guide to Choosing the Right In Situ Hybridization Method
This article provides a comprehensive comparison for researchers and drug development professionals between two powerful in situ hybridization (ISH) technologies: RNAscope and Hybridization Chain Reaction (HCR).
RNAscope vs. clampFISH: A Comprehensive Cost and Sensitivity Analysis for Spatial Biology
This article provides a decisive comparison for researchers and drug development professionals choosing between RNAscope and clampFISH for in situ hybridization.
Preventing Tissue Detachment in RNAscope: A Complete Guide for Reliable In Situ Hybridization
This comprehensive guide addresses the critical challenge of tissue detachment during RNAscope in situ hybridization procedures, a common frustration for researchers and drug development professionals.
RNAscope Sample Preparation Fixation: A Complete Guide for Reliable Gene Expression Analysis
This comprehensive guide details the critical role of fixation in RNAscope sample preparation for researchers and drug development professionals.
Mastering the RNAscope Assay: A Complete Guide to Optimized Protocol, Troubleshooting, and Validation for FFPE Tissues
This comprehensive guide details the RNAscope in situ hybridization protocol for Formalin-Fixed Paraffin-Embedded (FFPE) tissues, a critical technique for spatial transcriptomics in research and clinical diagnostics.
Integrated RNAscope and Immunohistochemistry Co-Detection: A Multi-Omics Guide for Spatial Biology
This article provides a comprehensive guide to RNA-protein integrated co-detection workflows, combining RNAscope in situ hybridization with immunohistochemistry (IHC) or immunofluorescence (IF).
RNAscope Detection Limit: Unlocking Single-Molecule RNA Sensitivity for Research and Diagnostics
This article provides a comprehensive analysis of the detection limit of RNAscope, a revolutionary in situ hybridization (ISH) technology.
Benchmarking scRNA-seq Platforms for Embryo Research: A Guide to Technology Selection and Experimental Optimization
Single-cell RNA sequencing has revolutionized our understanding of early embryonic development, providing unprecedented insights into lineage specification and cellular heterogeneity.
Cross-Species Embryo scRNA-seq: A New Frontier for Developmental Biology and Drug Discovery
Cross-species comparison of single-cell RNA sequencing (scRNA-seq) datasets from embryos is revolutionizing our understanding of developmental biology, disease origins, and evolutionary processes.
Breaking the Barrier: Advanced Strategies for High-Efficiency cDNA Amplification from Low-Input Embryo Samples
This article provides a comprehensive guide for researchers and drug development professionals tackling the critical challenge of cDNA amplification from precious, low-input embryonic samples.